The American journal of emergency medicine
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Comparative Study
Intravenous vs. intraosseous access and return of spontaneous circulation during out of hospital cardiac arrest.
Guidelines endorse intravenous (IV) and intraosseous (IO) medication administration for cardiac arrest treatment. Limited clinical evidence supports this recommendation. A multiagency, retrospective study was performed to determine the association between parenteral access type and return of spontaneous circulation (ROSC) in out of hospital cardiac arrest. ⋯ An IO first approach was non-inferior to an IV first approach based on the end point ROSC at time of emergency department arrival.