Resuscitation
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Biography Historical Article
Peter J. Safar. Part two. The University of Pittsburgh to the Safar Centre for Resuscitation Research 1961-2002.
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Randomized Controlled Trial Clinical Trial
The effect of seeing the rhythm display on performance of cardiopulmonary resuscitation.
Semiautomated external defibrillators are widely used by prehospital emergency personnel. Some of the devices have a rhythm display and some show only text commands on the screen. To evaluate the effects on cardiopulmonary resuscitation (CPR) performance of seeing the rhythm during resuscitation, 60 fire-fighter students were randomly divided in two groups and trained to use either a defibrillator with a rhythm display or one without a display. ⋯ The teams using a defibrillator with a rhythm display more often interrupted CPR for pulse checks than those who did not see the rhythm (P=0.003). The duration of CPR between rhythm analyses was shorter in the group who saw the rhythm on the screen (P=0.002). Our data suggest that seeing an organised rhythm on a monitor during CPR interferes with adherence to CPR algorithms which may have a negative influence on the performance of CPR.
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Defibrillation is essential for victims of sudden cardiac arrest (SCA) with ventricular fibrillation (VF), yet it does not terminate the underlying causes of VF. Prior to more definitive interventions, these same causes may result in recurrence of VF following defibrillation (refibrillation). The incidence and course of refibrillation, and its relation to patient outcomes, has not been previously described in the context of treatment of out-of-hospital SCA with biphasic waveform automated external defibrillators (AEDs). ⋯ One hundred and sixteen of 128 shocks delivered under BLS care to 49 patients with witnessed cardiac arrests presenting with VF terminated VF. Most patients (61%) refibrillated while under BLS care, many (35%) more than once. Occurrence of and time to refibrillation were unrelated to achievement of return of spontaneous circulation (ROSC) under BLS care (BLS ROSC), to survival to hospital discharge and to neurologically intact survival.
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The pupils dilate following cardiac arrest but the mechanism is unknown. If pupillary dilation represents inadequate blood supply to the midbrain, pupil size might be a rough guide to the adequacy of the resuscitation effort. The brain dead organ harvest patient presents a unique opportunity to study pupillary activity in the absence of an intact midbrain and to examine the effects of asphyxia on the pupil. ⋯ Time to peak dilation was 4.3+/-1.4 min and latency of dilation was 1.4+/-1.2 min. Dapiprazole eye drops prevented the pupillary dilation in contralateral eye of the five cases in which it was used. The cause of this sympathetic activity is either a short burst of neuronal activity in the peripheral sympathetic system innervating the dilator muscle, or release of stored norepinephine from the presynaptic terminals, as asphyxia intervenes.
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To assess the safety and the accuracy of a 4 h stepwise diagnostic approach relying on clinical judgement in unselected patients with acute chest pain. ⋯ The 4 h stepwise approach guided by clinical judgement was safe for ruling out impending cardiac events in unselected patients with acute chest pain. However, more extensive evaluation is necessary for accurate rule-in of coronary chest pain.