Resuscitation
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Randomized Controlled Trial Comparative Study
Randomised controlled trial of sustained lung inflation for resuscitation of preterm infants in the delivery room.
To compare the effects of sustained lung inflation (SLI) vs. standard resuscitation on physiologic responses of preterm infants during resuscitation. ⋯ SLI in infants who require respiratory support appears to be effective in facilitating postnatal transition as determined by HR and SpO2responses, resulting in less oxygen supplementation. Further studies are needed to confirm the benefits of SLI.
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Randomized Controlled Trial Multicenter Study
Time delays to reach dispatch centres in different regions in Europe. Are we losing the window of opportunity? - The EUROCALL study.
In out of hospital cardiac arrest (OHCA) the start of Cardiopulmonary Resuscitation (CPR) by a single rescuer may be delayed considerably if the total time (TT) to connect the telephone call to the Emergency Medical Communication Centre (EMCC) is prolonged. EUROCALL investigated the TT-EMCC and its components using different calling procedures. ⋯ TT-EMCC was significantly shorter in a 1-step procedure compared to a 2-step procedure. Regional differences existed between countries but also within countries. This may be relevant in cases of OHCA and other situations where patient outcome is critically time-dependent.
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Randomized Controlled Trial
Psychological wellbeing in survivors of cardiac arrest, and its relationship to neurocognitive function.
To characterise psychological wellbeing in survivors of out-of-hospital cardiac arrest (OHCA), and examine its relationship to cognitive function. ⋯ Anxiety plays an important role in determining perceived QoL in high functioning survivors, but psychological wellbeing is unrelated to cognitive function in this group. To achieve a comprehensive assessment of wellbeing, resuscitation research should consider outcomes beyond neurological function alone.
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Randomized Controlled Trial
Prophylactic versus clinically-driven antibiotics in comatose survivors of out-of-hospital cardiac arrest-A randomized pilot study.
To investigate benefits of prophylactic antibiotics in comatose survivors of out-of-hospital cardiac arrest (OHCA). ⋯ Bronchoscopy on admission documented tracheobronchial aspiration in 28% of comatose survivors of OHCA. In the absence of aspiration, prophylactic antibiotics did not significantly alter systemic inflammatory response, postresuscitation pneumonia, ICU treatment and outcome (ClinicalTrials.gov Identifier: NCT02899507).