Resuscitation
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Observational Study
Quantitative pupillometry and transcranial Doppler measurements in patients treated with hypothermia after cardiac arrest.
Predicting outcome after cardiac arrest (CA) is particularly difficult when therapeutic hypothermia (TH) is used. We investigated the performance of quantitative pupillometry and transcranial Doppler (TCD) in this context. ⋯ PLR measurements might be informative in the prediction of outcome of post-CA patients even under sedation and hypothermia.
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To date, 72% of variability in survival following out-of-hospital cardiac arrest (OHCA) is explained by the Utstein variables. Whether neighborhood factors further influence a return of spontaneous circulation or survival after OHCA is poorly understood. ⋯ Residential neighborhood factors marginally improve discrimination for outcomes after an OHCA, beyond the Utstein variables. Further research should explore the influence of other currently unmeasured neighborhood factors on OHCA outcomes.
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Review Meta Analysis
Comparing extracorporeal cardiopulmonary resuscitation with conventional cardiopulmonary resuscitation: A meta-analysis.
The objective was to determine whether extracorporeal cardiopulmonary resuscitation (ECPR), when compared with conventional cardiopulmonary resuscitation (CCPR), improves outcomes in adult patients, and to determine appropriate conditions that can predict good survival outcome in ECPR patients through a meta-analysis. ⋯ Survival and good neurologic outcome tended to be superior in the ECPR group at 3-6 months after arrest. The effect of ECPR on survival to discharge in OHCA was not clearly shown. As ECPR showed better outcomes than CCPR in studies with pre-defined criteria, strict indications criteria should be considered when implementation of ECPR.
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Observational Study
The influences of adrenaline dosing frequency and dosage on outcomes of adult in-hospital cardiac arrest: A retrospective cohort study.
To investigate the influence of dosing frequency and dosage of adrenaline on outcomes of cardiopulmonary resuscitation (CPR). ⋯ Higher adrenaline average dosing frequency may be associated with worse outcomes after CPR. Besides, according to current recommendations, patients with BW above 82.5kg may not receive adequate dose of adrenaline.