Journal of vascular surgery
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Randomized Controlled Trial Clinical Trial
Reduction in cardiovascular events after vascular surgery with atorvastatin: a randomized trial.
This prospective, randomized, placebo-controlled, double-blind clinical trial was performed to analyze the effect of atorvastatin compared with placebo on the occurrence of a 6-month composite of cardiovascular events after vascular surgery. Cardiovascular complications are the most important cause of perioperative morbidity and mortality among patients undergoing vascular surgery. Statin therapy may reduce perioperative cardiac events through stabilization of coronary plaques. ⋯ Short-term treatment with atorvastatin significantly reduces the incidence of major adverse cardiovascular events after vascular surgery.