European journal of anaesthesiology
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Randomized Controlled Trial Clinical Trial
Prophylactic intravenous bolus ephedrine for elective Caesarean section under spinal anaesthesia.
To evaluate the efficacy and optimal dose of prophylactic intravenous ephedrine for the prevention of maternal hypotension associated with spinal anaesthesia for Caesarean section. ⋯ A prophylactic bolus of ephedrine 12 mg intravenously given at the time of intrathecal block, plus rescue boluses, leads to a lower incidence of hypotension following spinal anaesthesia for elective Caesarean section compared to intravenous rescue boluses alone.
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Randomized Controlled Trial Clinical Trial
Magnesium infusion reduces perioperative pain.
Magnesium has antinociceptive effects in animal and human models of pain. These effects are primarily based on the regulation of calcium influx into the cell. The aim of this study was to determine whether perioperative infusion of magnesium would reduce postoperative pain and anxiety. ⋯ Continuous magnesium infusion, including the pre-, intra-, and postoperative periods reduces analgesic requirements. These results demonstrate that magnesium can be an adjuvant for perioperative analgesic management.
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Randomized Controlled Trial Clinical Trial
The prevention of propofol injection pain by tramadol or ondansetron.
To compare the efficacy of tramadol and ondansetron in minimizing the pain due to injection of propofol in 100 patients. ⋯ Tramadol or ondansetron are equally effective in preventing pain from propofol injection. The added benefit of a reduction in nausea and vomiting after operation in the ondansetron group may be a reason to prefer this drug.