European journal of anaesthesiology
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Letter Randomized Controlled Trial Comparative Study
Intraoperative epidural analgesia does not reduce time of postoperative analgesic treatment compared to intravenous analgesia.
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Combined spinal-epidural analgesia is effective in labour analgesia. Nitric oxide may play important roles in pregnancy and labour and is probably affected by labour pain. The aim of the present study was to explore the alteration in serum levels of nitric oxide metabolites, i.e. nitrate and nitrite, during labour with or without combined spinal-epidural analgesia. ⋯ Combined spinal-epidural analgesia provided effective analgesia and abolished the decrease in nitric oxide metabolites during active labour.