European journal of anaesthesiology
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Randomized Controlled Trial
Lidocaine given intravenously improves conditions for laryngeal mask airway insertion during propofol target-controlled infusion.
Patient response to laryngeal mask airway insertion during propofol induction depends on many factors. Lidocaine has been used to reduce cardiovascular responses, coughing, and bucking induced by tracheal intubation. The aim of this study was to determine the effects of intravenous lidocaine on laryngeal mask airway insertion conditions during the induction of anaesthesia with propofol target-controlled infusion. ⋯ Pretreatment with intravenous lidocaine 1.5 mg kg during induction with propofol target-controlled infusion improves laryngeal mask airway insertion conditions.
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Randomized Controlled Trial Comparative Study
Intraabdominal local anaesthetics for postoperative pain relief following abdominal hysterectomy: a randomized, double-blind, dose-finding study.
Local anaesthetics administered intraabdominally have been found to reduce analgesic requirements postoperatively after hysterectomy. This study was designed to assess the optimal dose of local anaesthetics for best pain relief. ⋯ Satisfactory analgesia can be achieved with low doses of levobupivacaine administered intraabdominally, except during the early postoperative period. No advantages were seen in this study when higher doses of levobupivacaine were administered as a continuous infusion for postoperative pain relief.
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Prolonged mechanical ventilation (PMV) after heart surgery is associated with increased patient morbidity and mortality. ⋯ This review allowed us to assess predictors, helping us to identify 'a priori' patients more likely to undergo PMV.
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Randomized Controlled Trial Comparative Study
Auditory function after spinal anaesthesia: the effect of differently designed spinal needles.
Recurrent, bilateral or unilateral, persistent or transient, mild or profound hearing loss has been reported after spinal anaesthesia. We studied the effects of the needle type (Quincke, ballpen, pencil-point spinal needles) on hearing loss after spinal anaesthesia with the use of pure-tone audiometry. ⋯ Because the use of ballpen and pencil-point needles reduces hearing loss after spinal anaesthesia, these needles are preferred.
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Comparative Study Controlled Clinical Trial
PAI-1 gene: pharmacogenetic association of 4G/4G genotype with bleeding after cardiac surgery--pilot study.
To investigate whether the 4G/4G genotype of the PAI-1 gene is associated with bleeding after cardiac surgery and whether it may influence the use of antifibrinolytic drugs. ⋯ The 4G/4G genotype of the PAI-1 gene was associated with less bleeding after cardiac surgery only in the subgroup of patients treated with aprotinin.