European journal of anaesthesiology
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Randomized Controlled Trial
Spinal anaesthesia with low-dose bupivacaine in marginally hyperbaric solutions for caesarean section.
Conventional hyperbaric spinal anaesthesia solution (SAS) with 8% glucose and low-dose bupivacaine may reduce the incidence of hypotension in caesarean section compared to standard doses, and marginally hyperbaric SAS (≤0.8% glucose) can induce a lower block level and a lower incidence of hypotension in nonobstetric patients than conventional 8% glucose SAS. ⋯ Compared with conventional 8% glucose hyperbaric SAS, marginally hyperbaric (0.5 or 0.33% glucose) low-dose bupivacaine solutions led to a significantly lower height of cephalad spread and incidence of hypotension with no impact on the efficacy of spinal anaesthesia for caesarean section.
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Multicenter Study Observational Study
Development and validation of a score to predict postoperative respiratory failure in a multicentre European cohort: A prospective, observational study.
Postoperative respiratory failure (PRF) is the most frequent respiratory complication following surgery. ⋯ A risk score based on seven objective, easily assessed factors was able to predict which patients would develop PRF. The score could potentially facilitate preoperative risk assessment and management and provide a basis for testing interventions to improve outcomes.The study was registered at ClinicalTrials.gov (identifier NCT01346709).