Family practice
-
Review Meta Analysis
Increased risk for atypical fractures associated with bisphosphonate use.
Studies suggest an increasing occurrence of atypical femoral fractures with the use of bisphosphonates. ⋯ Results suggest there is an increased risk for atypical fractures associated with bisphosphonates and raises awareness to the potential complications related with bisphosphonates. These findings warrant the comprehensive evaluation of patients before initiating bisphosphonate therapy and highlights the need for additional medical decision analyses in future studies to compare the benefit over potential harms of bisphosphonate therapy.