Anaesthesia and intensive care
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Anaesth Intensive Care · Jun 1996
Randomized Controlled Trial Comparative Study Clinical TrialThe application of EMLA and glyceryl trinitrate ointment prior to venepuncture.
The efficacy of EMLA cream combined with glyceryl trinitrate (GTN) ointment was assessed by a double-blind prospective study. Adult female patients were randomly allocated to receive either EMLA 1 ml or 2 ml combined with GTN 2 mg, or EMLA 2 ml only. ⋯ There were no significant side-effects. It is concluded that if GTN is used with EMLA, the dose of EMLA can be reduced and intravenous cannulation is technically easier compared with EMLA alone.
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Anaesth Intensive Care · Jun 1996
Randomized Controlled Trial Comparative Study Clinical TrialComparison of subcutaneous ring block of the penis with caudal epidural block for post-circumcision analgesia in children.
A randomized, prospective, blind trial was conducted comparing caudal epidural blockade (caudal block) with subcutaneous ring block of the penis (penile ring block) in fifty healthy boys between two and twelve years of age undergoing elective circumcision. Subjects receiving caudal block had a longer duration of analgesia (P = 0.003), and took longer to first micturition (P = 0.04) but there was no difference in time taken to awaken from anaesthesia or spontaneously walk unaided. ⋯ It is concluded that both techniques are effective. Caudal block is more reliable and produces a longer duration of analgesia but penile ring block is inherently safer and has a lower incidence of adverse effects.