Anaesthesia and intensive care
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Anaesth Intensive Care · May 2021
Randomized Controlled TrialEfficacy of different infusion rates of oxytocin for maintaining uterine tone during elective caesarean section: A randomised double blind trial.
Most research in this field has focused on finding oxytocin doses for initiating uterine contractions. Only limited data are available regarding the optimal rate of oxytocin infusion to maintain adequate uterine tone. This randomised, double blind study included 120 healthy term pregnant patients with uncomplicated, singleton pregnancy undergoing elective caesarean section under spinal anaesthesia. ⋯ The incidence of tachycardia (P = 0.726), hypotension (P = 0.321) and nausea/vomiting (P = 0.161) was comparable. To conclude, 5 IU/hour was more effective than 1.25 IU/hour in reducing total blood loss and the incidence of minor postpartum haemorrhage. Thus 5 IU/hour appears to be an optimal oxytocin infusion rate following 1 IU slow intravenous oxytocin injection for the maintenance of adequate uterine contraction in patients undergoing elective caesarean section under spinal anaesthesia.
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Anaesth Intensive Care · May 2021
Letter Randomized Controlled TrialSurvey of attitudes towards a randomised trial about sugammadex, neostigmine and pulmonary complications.