The Clinical journal of pain
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Randomized Controlled Trial Meta Analysis Comparative Study Clinical Trial
The time to onset and overall analgesic efficacy of rofecoxib 50 mg: a meta-analysis of 13 randomized clinical trials.
To determine the time to onset of analgesia of rofecoxib based on a patient-level meta-analysis of randomized, placebo-controlled, postoperative oral surgery pain studies. ⋯ In this meta-analysis of over 1200 rofecoxib-treated patients, a single dose of rofecoxib 50 mg demonstrated a rapid onset of analgesia in approximately half an hour combined with sustained effectiveness, supporting its use as a treatment of acute pain.
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Randomized Controlled Trial Comparative Study Clinical Trial
Physicians' assessments versus measured symptoms of complex regional pain syndrome type 1: presence and severity.
To assess the validity of physician's judgements of symptoms associated with Complex Regional Pain Syndrome Type 1. ⋯ We conclude that establishing the presence of Complex Regional Pain Syndrome Type 1 symptoms, except for temperature and volume asymmetries, and monitoring of disease progression based on these symptoms can be performed by clinical judgment. The severity of the individual symptoms evaluated in this study should be measured with reliable and valid measurement instruments.
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Randomized Controlled Trial Comparative Study Clinical Trial
Pain report and pain-related evoked potentials operantly conditioned.
The purpose of the present study was to answer the question whether pain report can be increased and decreased by operant conditioning. We predicted that the conditioned pain effects would remain significant after correction for social desirability and fantasy proneness. Furthermore, we tried to show that the neurophysiologic basis of verbal pain report, defined by pain (event)-related potentials, was affected by the conditioning procedure. Specifically, it was expected that the central recording site N150-P260 pain (event)-related potentials peak-to-peak amplitude would show the largest effect. ⋯ We concluded that the subjective report of pain as well as a specific pain-related potentials component can be operantly conditioned.
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Comparative Study
Self-report and pain behavior among patients with chronic pain.
To determine the relationship between pain behaviors and self-report of pain and disability in patients with chronic pain. ⋯ Findings suggest that pain behavior observation is a valid and reliable assessment tool for use with a heterogeneous chronic pain population. Significant associations were found between pain behaviors and self-report measures of pain intensity, pain disability, and self-efficacy; pain intensity scores displayed a weak relationship; and pain disability scores the strongest relationship with pain behavior. Viewed with previous research, the results of this study indicate the value of a multimodal, cognitive-behavioral approach to assessing patients with chronic pain.
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Comparative Study
The differential influence of pain and fatigue on physical performance and health status in ambulatory patients with human immunodeficiency virus.
The purposes of this study were to: 1) characterize physical performance in individuals with human immunodeficiency virus; and 2) examine group differences by pain and fatigue on a multivariate profile of disease, physical, and psychologic symptoms. ⋯ Pain has a substantial impact on physical performance and quality of life among ambulatory human immunodeficiency virus patients. Fatigue also impacts physical performance. Compromised ability to perform certain physical tasks affects quality of life. Further investigation of the roles of these relevant variables should be investigated in path analyses.