The Clinical journal of pain
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Randomized Controlled Trial Clinical Trial
Documented and self-reported child abuse and adult pain in a community sample.
To examine the association of chronic pain in young adults with childhood exposure to maltreatment and to determine whether depressive symptoms mediate such an association. ⋯ Overall, results show an association between self-reported sexual abuse history and adult pain complaints in this general population sample, which was not attributable to symptoms of depression at the time of such reports.
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Randomized Controlled Trial Comparative Study Clinical Trial
The responses to pharmacological challenges and experimental pain in patients with chronic whiplash-associated pain.
This study evaluates the analgesic responses to intravenous administration of morphine, lidocaine, and ketamine and their relations to duration of chronic pain after whiplash trauma. In addition, experimental muscle pain sensitivity and its correlation to pain duration and pharmacological responses were assessed. ⋯ The pharmacological challenges identified subgroups of patients with chronic whiplash-associated disorder that might be considered before instituting therapeutic interventions or research. However, the pattern of responses to the pharmacological challenges did not show any clear relationships with pain duration or the experimental pain tests.