The Clinical journal of pain
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Randomized Controlled Trial
Evaluation of the analgesic efficacy of local dexmedetomidine application.
To determine the analgesic effects of locally applied dexmedetomidine in third molar surgery under general anesthesia. ⋯ Dexmedetomidine seems to have an antihyperalgesic effect when administered locally after bilateral third molar surgery. There is no delay in psychomotor recovery or increase in postoperative clinically significant adverse events.
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Randomized Controlled Trial Comparative Study
Subjective well-being in patients with chronic tension-type headache: effect of acupuncture, physical training, and relaxation training.
Episodic tension-type headache is a common problem affecting approximately 2 of 3 of the population. The origin of tension-type headache is multifactorial, but the pathogenesis is still unclear. In some individuals episodic tension-type headache transforms into chronic tension-type headache (CTTH). Subjective symptoms related to the central nervous system might affect patients subjective well-being and quality of life. ⋯ Physical training and relaxation training seem to be preferable nonpharmacologic treatments for improvement of central nervous system-related symptoms and subjective well-being for patients with CTTH.
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Randomized Controlled Trial
Effectiveness of leech therapy in chronic lateral epicondylitis: a randomized controlled trial.
Leech therapy has been found to be effective in osteoarthritis of the knee and hand in previous trials. Chronic epicondylitis is a prevalent pain syndrome with limited treatment options. In this study, we tested whether leech therapy would be beneficial in the symptomatic treatment of chronic lateral epicondylitis. ⋯ A single course of leech therapy was effective in relieving pain in the short-term and improved disability in intermediate-term. Leeches might be considered as an additional option in the therapeutic approach to lateral epicondylitis.
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Randomized Controlled Trial
Effectiveness of a psychoeducational treatment program implemented in general practice for fibromyalgia patients: a randomized controlled trial.
A recent meta-analysis concluded that multicomponent treatments are effective for some fibromyalgia (FM) symptoms. The objective of this study was to examine whether a psychoeducational intervention implemented in primary care is more effective than usual care for improving the functional status of patients with FM. ⋯ A 2-month psychoeducational intervention improves the functional status of FM patients to a greater extent than usual care, at least in the short-term. The social desirability bias did not explain the reported outcomes. Trait anxiety was associated with response to treatment.
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Randomized Controlled Trial
Differential frequency effects of strong nonpainful transcutaneous electrical nerve stimulation on experimentally induced ischemic pain in healthy human participants.
Electrophysiological studies show frequency-dependent effects of transcutaneous electrical nerve stimulation (TENS) in animal models of hyperalgesia. Evidence of frequency-dependent effects of TENS in humans is conflicting. ⋯ Strong nonpainful TENS delivered at 80 pps reduced experimentally induced ischemic pain when compared with TENS delivered at 3 pps.