The Clinical journal of pain
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    Review Meta AnalysisEffects of Combining Dexmedetomidine and Opioids for Postoperative Intravenous Patient-controlled Analgesia: A Systematic Review and Meta-analysis.This meta-analysis evaluated the effects of opioid-dexmedetomidine (DEX) combinations for postoperative patient-controlled analgesia (PCA). ⋯ These data suggest that an opioid-DEX combination is a safe and effective strategy for postoperative intravenous PCA.