The Clinical journal of pain
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Electronic pain measures are becoming common tools in the assessment of pediatric pain intensity. The aims of this study were (1) to examine the agreement between the verbal and the electronic versions of the 11-point Numerical Rating Scale (NRS-11) (vNRS-11 and eNRS-11, respectively) when used to assess pain intensity in adolescents; and (2) to report participants' preferences for each of the 2 alternatives. ⋯ Pain intensity ratings on the vNRS-11 and eNRS-11 seem to be comparable, at least for the 80% CI.
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To identify psychological covariates of longitudinal changes in back-related disability in patients undergoing acupuncture. ⋯ Illness perceptions and, to a lesser extent, self-efficacy and expectancies can usefully supplement variables from the fear-avoidance model in theorizing pain-related disability. Positive changes in patients' beliefs about back pain might underpin the large nonspecific effects of acupuncture seen in trials and could be targeted clinically.
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The aim of this cohort study was to investigate the association between self-reported cardiovascular disorders (CVD) and recovery from whiplash-associated disorder (WAD) after a traffic collision. ⋯ Our results suggest that CVD does not have an impact on the recovery of individuals with WAD.
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The objectives of this study are (1) to assess the presence of myofascial trigger points (TrPs) and widespread pressure hyperalgesia; and (2) to assess the relationship between the presence of active TrPs, pain intensity, and widespread pressure hypersensitivity in individuals with postmeniscectomy pain. ⋯ The referred pain elicited by active TrPs reproduced knee symptoms in patients with postmeniscectomy pain. Patients also showed localized reduction of PPT. The number of TrPs was associated with the intensity of pain and pressure hyperalgesia. Our findings suggest the presence of peripheral sensitization in patients with postmeniscectomy pain could be associated with the presence of active TrPs.
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To begin to address the problem of heterogeneity of distribution of oxycodone (OC) in humans, we developed an organ-specific microcirculatory capillary-tissue exchange 2-compartment model for studying regional OC mass transport. ⋯ Organ-specific OC mass transport kinetics provide new information for OC dosing in pain management. The model promotes patient safety in opioid prescribing because it allows predictions to be made about the relative contribution that OC recycling makes to circulating OC levels. The model indicates that pharmacologic modulation of the microcirculation may give way to site-specific delivery of opioids in the future. Our study demonstrates that translation of bench in silico research data into clinical practice, although still challenging, is feasible and can assist in OC dose regimen design for patient safety.