The Clinical journal of pain
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Randomized Controlled Trial Multicenter Study
Pregabalin Improves Fibromyalgia-Related Sleep Disturbance.
To investigate the effect of pregabalin on wake and sleep bout parameters. ⋯ Pregabalin improved sleep parameters characteristic of disturbed sleep in FM, by preventing awakenings and increasing sleep bout duration. These effects are reflected in, and correlated with, a decrease in "light sleep" (stage 1) and an increase in "deep sleep" (slow wave sleep).