The Clinical journal of pain
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Randomized Controlled Trial Multicenter Study
Patient-Controlled Intravenous Analgesia with Combination of Dexmedetomidine and Sufentanil on Patients after Abdominal Operation: A Prospective, Randomized, Controlled, Blinded, Multicenter Clinical Study.
To investigate the effect of combination of dexmedetomidine and sufentanil on patient-controlled intravenous analgesia (PCIA) in patients after abdominal operation and to assess the safety and validity of this treatment. ⋯ Compared with sufentanil PCIA alone, the combination of dexmedetomidine and sufentanil for PCIA after abdominal operation could reduce sufentanil consumption, decrease VAS scores, lower the rate of nausea and vomiting, and improve patient satisfaction.
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Randomized Controlled Trial Multicenter Study
Opioid-sparing Effects of SoluMatrix Indomethacin in a Phase 3 Study in Patients with Acute Postoperative Pain.
To report the opioid-sparing effects of SoluMatrix indomethacin, developed using SoluMatrix Fine Particle Technology, in a phase 3 study in patients with acute pain following bunionectomy. ⋯ SoluMatrix indomethacin was associated with opioid-sparing effects in patients with acute postoperative pain.