The Clinical journal of pain
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Meta Analysis
An Updated Systematic Review and Meta-analysis of Duloxetine for Knee Osteoarthritis Pain.
We conducted the updated systematic review and meta-analysis of the best available quantitative and qualitative evidence to evaluate the effects and safety of duloxetine for the treatment of knee osteoarthritis (OA) pain. ⋯ Duloxetine may be an effective treatment option for knee OA patients but further rigorously designed and well-controlled randomized trials are warranted.
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Meta Analysis
Quality of Life Related to Functional Disability in Migraine Patients: A Systematic Review and Network-meta Analysis.
The aim of this study was to conduct a systematic review and network meta-analysis of all randomized trials investigating effect of anti-calcitonin gene-related peptide monoclonal antibodies on disability related to migraine in adult patients. ⋯ For short-term prevention of migraine, fremanezumab demonstrated slightly better improvement in disability compared with other anti-calcitonin gene-related peptide monoclonal antibodies in adult patients with migraine.