The Clinical journal of pain
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Randomized Controlled Trial
Exploration and Validation of the Behavioural Pain Measures and Physiological Pain Measures Factor Structure Extracted from the Pain Assessment Tool Item Scores for Infants Admitted to Neonatal Intensive Care.
The objective of the study was to explore and then validate the factor structure of the Pain Assessment Tool (PAT). ⋯ The PAT assesses both Behavioral Pain and Physiological Pain Measures, and these dimensions need to be considered separately when assessing pain in infants in the neonatal intensive care unit. Behavioral item scores may be insufficient for detecting pain in premature infants if used alone.
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Randomized Controlled Trial Multicenter Study
The Effect of Epidural Nalbuphine Combined with Ropivacaine on Epidural Analgesia During Labor-- A Multicenter, Randomized, Double-blind, Controlled Study.
The addition of a small dose of opioids during epidural labor analgesia can enhance the local analgesic effect, reduce the dose of local anaesthetic required, and minimize motor blockade. For the treatment of visceral pain, studies have shown that κ-opioid receptor agonist are more effective than μ-receptor agonists. This study compared the effectiveness of epidural nalbuphine and sufentanil in combination with ropivacaine for labor analgesia, respectively. ⋯ The analgesia effects of 0.3 mg/mL nalbuphine with ropivacaine are inferior to 0.3 μg/mL sufentanil with ropivacaine in labor analgesia. No serious side effects, either in the mother or in the fetus, were observed.