Pediatric emergency care
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Pediatric emergency care · Apr 2002
Randomized Controlled Trial Comparative Study Clinical TrialComparison of two benzodiazepines used for sedation of children undergoing suturing of a laceration in an emergency department.
(1) To determine if oral diazepam (POD) is as effective in sedating children less than 6 years of age for laceration repair as oral midazolam (POM) or intranasal midazolam (INM); and (2) To determine if patients stayed longer in the department after sedation when given POD for sedation. ⋯ The oral route of delivery of POM and POD was better tolerated than INM. POM and INM were more effective at sedation than POD, but there was no clinical difference between any groups for time to sedation or time to discharge. More patients in the POM group had side effects after leaving the department. POD may be an alternative to POM, but a higher dose may be required, possibly with longer recovery times.