The British journal of psychiatry : the journal of mental science

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• Br J Psychiatry · Apr 2010

  Randomized Controlled Trial

  Cost-effectiveness of a stepped care intervention to prevent depression and anxiety in late life: randomised trial.

  There is an urgent need for the development of cost-effective preventive strategies to reduce the onset of mental disorders. ⋯ The prevention programme generated depression- and anxiety-free survival years in the older population at affordable cost.

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• Br J Psychiatry · Apr 2010

  Randomized Controlled Trial

  Economic evaluation of online computerised cognitive-behavioural therapy without support for depression in primary care: randomised trial.

  Evidence about the cost-effectiveness and cost utility of computerised cognitive-behavioural therapy (CCBT) is still limited. Recently, we compared the clinical effectiveness of unsupported, online CCBT with treatment as usual (TAU) and a combination of CCBT and TAU (CCBT plus TAU) for depression. The study is registered at the Netherlands Trial Register, part of the Dutch Cochrane Centre (ISRCTN47481236). ⋯ On balance, CCBT constitutes the most efficient treatment strategy, although all treatments showed low adherence rates and modest improvements in depression and quality of life.

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