Pediatric neurology
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Pediatric neurology · Jan 2014
Review Case ReportsLambert-Eaton syndrome, an unrecognized treatable pediatric neuromuscular disorder: three patients and literature review.
Lambert-Eaton myasthenic syndrome, a presynaptic neuromuscular junction autoimmune disorder, rarely occurs in children. Patients typically present with proximal lower extremity weakness with areflexia. ⋯ Lambert-Eaton myasthenic syndrome is a diagnosis that must be considered in children presenting with unidentified proximal muscle weakness. In most children, Lambert-Eaton myasthenic syndrome is a primary autoimmune disorder that is treatable. Nevertheless, a search for malignancy is recommended.