Diabetes research and clinical practice
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Diabetes Res. Clin. Pract. · Sep 2012
Randomized Controlled Trial Multicenter StudyA gastroretentive gabapentin formulation for the treatment of painful diabetic peripheral neuropathy: efficacy and tolerability in a double-blind, randomized, controlled clinical trial.
A randomized, double-blind, placebo-controlled study was conducted in 147 patients to determine the efficacy and safety of a gastroretentive formulation of gabapentin (G-GR) in treating painful diabetic peripheral neuropathy (DPN). ⋯ Once-daily G-GR was effective and well tolerated for the treatment of pain due to DPN.