Diabetes research and clinical practice
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Diabetes Res. Clin. Pract. · Apr 2015
Randomized Controlled Trial Multicenter StudyHow well do glucose variability measures predict patient glycaemic outcomes during treatment intensification in type 2 diabetes?
Despite links to clinical outcomes in patients with type 2 diabetes mellitus (T2DM), the clinical utility of glycaemic variability (GV) measures is unknown. We evaluated the correlation between baseline GV, and glycated haemoglobin (HbA1c) attainment and hypoglycaemic events during treatment intensification in a large group of patients. ⋯ Pre-treatment GV is associated with glycaemic outcomes in T2DM patients undergoing treatment intensification over 24 weeks. HBGI might be the most robust predictor, warranting validation in dedicated prospective studies or randomized trials to assess the predictive value of measuring GV.
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Diabetes Res. Clin. Pract. · Apr 2015
Multicenter StudyRelationship between primary care visits and hospital admissions in remote Indigenous patients with diabetes: a multivariate spline regression model.
To determine if access to primary health care (PHC) is associated with reduced hospitalisations for remote Indigenous patients with diabetes. ⋯ Using existing empirical data, this study suggests that other things being equal, diabetes patients who had an adequate level of PHC visits are likely to have a lower level of hospitalisations than those with fewer or more PHC visits. This study highlights the importance for remote Indigenous patients with diabetes to have adequate access to PHC.
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Diabetes Res. Clin. Pract. · Apr 2015
Multicenter StudyRace/ethnicity moderates the relationship between chronic life stress and quality of life in type 2 diabetes.
To determine whether chronic life stress is differentially associated with quality of life (QoL) for Blacks vs. Hispanics with type 2 diabetes. ⋯ Black patients with type 2 diabetes may be particularly vulnerable to the deleterious effects of high chronic stress. Social support buffers effects of stress on mental health in Hispanics but not Blacks, which suggests differences in the use and/or quality of social support between Hispanics and Blacks. Longitudinal investigations that examine race/ethnicity, stress, social support, and QoL should help clarify the processes that underlie these observed relations.