Pediatric pulmonology
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Pediatric pulmonology · Oct 2013
Review Case ReportsVariable clinical outcome of ABCA3 deficiency in two siblings.
This case report describes an unusual outcome of ABCA3 deficiency with resolution of symptoms, normalization of chest imaging and lung function in a 9-year-old child whose sibling died of the same disease in infancy.
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Pediatric pulmonology · Oct 2013
Abnormal infant pulmonary function in young children with neuroendocrine cell hyperplasia of infancy.
Lung function in children with neuroendocrine cell hyperplasia of infancy (NEHI) and correlations with future clinical outcomes are needed to guide clinical management. ⋯ IPFTs in NEHI subjects are feasible, demonstrate significant obstruction and air trapping, and correlate with future RA O2 sat and FEV1 . IPFTs may provide valuable clinical information when caring for NEHI patients. Pediatr Pulmonol. 2013; 48:1008-1015. © 2012 Wiley Periodicals, Inc.
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Pediatric pulmonology · Oct 2013
Comparative StudyAlbuterol delivery via metered dose inhaler in a spontaneously breathing pediatric tracheostomy model.
Little data are available regarding efficiency of drug delivery devices and techniques despite their widespread use in spontaneously breathing tracheostomized patients. We compared patient dose achieved with different devices, inhalation techniques, tracheostomy tube sizes and breathing patterns using a spontaneously breathing tracheostomized pediatric model. ⋯ Aerotrach Plus and the adapter were the most and least efficient devices respectively. Tracheostomy size and breathing pattern affected drug delivery. The use of assisted technique reduced aerosol delivery.