Pediatric pulmonology
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Pediatric pulmonology · Dec 2015
Randomized Controlled TrialExperimentally manipulated sleep duration in adolescents with asthma: Feasibility and preliminary findings.
To examine the impact of sleep duration on lung function and asthma symptoms in adolescents. ⋯ This pilot study demonstrated the feasibility of a cross-over sleep manipulation protocol in adolescents with asthma. Since overnight decrease in PEFR is a marker of nocturnal asthma, and has been associated with the severity of daytime airflow limitation, these early-stage results suggest that shortened sleep duration may exacerbate adolescent asthma and associated functional impairments.
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Pediatric pulmonology · Dec 2015
Randomized Controlled TrialNebulized magnesium for moderate and severe pediatric asthma: A randomized trial.
Intravenous magnesium sulfate, a rescue therapy added to bronchodilator and systemic steroid therapy for moderate and severe asthma, is uncommonly administered. We hypothesized that nebulized magnesium would confer benefit without undue risk. ⋯ Adding nebulized magnesium to combined nebulized bronchodilator and systemic steroid therapy failed to significantly shorten time to discharge of pediatric patients with moderate or severe asthma.