Pediatric pulmonology
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Pediatric pulmonology · Feb 2015
Mannose-binding lectin 2 gene polymorphism and lung damage in primary ciliary dyskinesia.
Mannose-binding lectin (MBL) plays an important role in innate immunity and has been reported to be associated with the age-related decline in lung function in cystic fibrosis. ⋯ MBL plays a relatively minor role as a disease modifier in PCD. A similar finding in SCD supports the likely significance of this result.