Pediatric pulmonology
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Pediatric pulmonology · Mar 2018
Randomized Controlled Trial Multicenter StudyNebulized hypertonic saline in infants hospitalized with moderately severe bronchiolitis due to RSV infection: A multicenter randomized controlled trial.
The efficacy of nebulized hypertonic saline (HS) therapy for shortening hospital length of stay (LOS) or improving bronchiolitic symptoms remains controversial. Most studies enrolled small numbers of subjects and did not consider the role of respiratory syncytial virus (RSV), the most common cause of acute bronchiolitis. Our aim was to evaluate the efficacy and safety of nebulized HS therapy for acute bronchiolitis due to RSV in moderately ill hospitalized infants. ⋯ Nebulized HS therapy did not significantly reduce LOS among infants with bronchiolitis due to RSV.
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Pediatric pulmonology · Mar 2018
Regional lung function testing in children using electrical impedance tomography.
To evaluate regional lung function in lung-healthy children before and after exercise challenge using electrical impedance tomography (EIT). ⋯ Global and regional lung functions were not affected by exercise in lung-healthy children. Exercise did not increase ventilation inhomogeneity. The obtained EIT-derived regional lung parameters can serve as reference values for future studies in children with lung diseases.