Scandinavian journal of primary health care
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Scand J Prim Health Care · Sep 2007
Randomized Controlled Trial Comparative StudyEffects of treatment with a commercially available St John's Wort product (Movina) on cholesterol levels in patients with hypercholesterolemia treated with simvastatin.
To assess the effect of treatment with a St John's Wort product (Movina) on cholesterol levels (total cholesterol, LDL-cholesterol, and HDL-cholesterol) in patients with hypercholesterolemia on treatment with a stable dose of simvastatin. ⋯ Products containing St John's Wort should not be given to patients with hypercholesterolemia who are on treatment with simvastatin.
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Scand J Prim Health Care · Sep 2007
Randomized Controlled Trial Comparative StudyRecognition of fasting or overall hyperglycaemia when starting insulin treatment in patients with type 2 diabetes in general practice.
The efficacy of various regimens of initial insulin treatment in poorly controlled type 2 diabetes was compared with regard to diurnal glucose variation. ⋯ Not all poorly controlled type 2 diabetic patients should automatically be treated with an oral agent and bedtime insulin. Two daily insulin injections is a valid choice, particularly if the patient has overall hyperglycaemia.