Scandinavian journal of primary health care
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Scand J Prim Health Care · Jan 2008
Randomized Controlled TrialEffects of anti-secretory factor (ASF) on irritable bowel syndrome (IBS). A double-blind, randomized study.
To evaluate the role of the endogenous protein anti-secretory factor (ASF) on the symptoms, especially loose stools, in irritable bowel ayndrome (IBS). ⋯ Both study groups improved significantly on the VAS but no additive effect was seen for the active treatment. In the sub-group with loose stools, the SPC diet induced ASF plasma levels in IBS patients and was correlated to significant symptom improvement in the individual patient.
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Scand J Prim Health Care · Sep 2007
Randomized Controlled Trial Comparative StudyRecognition of fasting or overall hyperglycaemia when starting insulin treatment in patients with type 2 diabetes in general practice.
The efficacy of various regimens of initial insulin treatment in poorly controlled type 2 diabetes was compared with regard to diurnal glucose variation. ⋯ Not all poorly controlled type 2 diabetic patients should automatically be treated with an oral agent and bedtime insulin. Two daily insulin injections is a valid choice, particularly if the patient has overall hyperglycaemia.
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Scand J Prim Health Care · Sep 2007
Randomized Controlled Trial Comparative StudyEffects of treatment with a commercially available St John's Wort product (Movina) on cholesterol levels in patients with hypercholesterolemia treated with simvastatin.
To assess the effect of treatment with a St John's Wort product (Movina) on cholesterol levels (total cholesterol, LDL-cholesterol, and HDL-cholesterol) in patients with hypercholesterolemia on treatment with a stable dose of simvastatin. ⋯ Products containing St John's Wort should not be given to patients with hypercholesterolemia who are on treatment with simvastatin.
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Scand J Prim Health Care · Mar 2007
Randomized Controlled Trial Multicenter Study Comparative StudyClinical and bacteriological outcome of different doses and duration of pivmecillinam compared with placebo therapy of uncomplicated lower urinary tract infection in women: the LUTIW project.
To analyse associations between symptoms and bacteriuria in uncomplicated lower urinary tract infection in women (LUTIW) and to evaluate outcome of therapy with three different regimens of pivmecillinam or placebo. ⋯ Symptoms are not conclusive for diagnosis of LUTIW. Pivmecillinam therapies are superior to placebo and seven days regimens are more efficient than three days. Pivmecillinam 200 mg x 2 x 7 days is recommended as a first-line therapy for LUTIW.
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Scand J Prim Health Care · Jun 2006
Randomized Controlled TrialClinical course of suspected viral sore throat in young adults: cohort study.
To evaluate the natural clinical course of suspected viral sore throat. ⋯ Almost all the patients had recovered by day 8. A high correlation was found between sickness and sore throat. These data will assist clinicians and others promoting self-care to set realistic expectations regarding recovery from URTI in young adults.