The Journal of international medical research
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Randomized Controlled Trial
Effect of inhalational anaesthetic on postoperative cognitive dysfunction following radical rectal resection in elderly patients with mild cognitive impairment.
To determine the effect of choice of inhalational anaesthetic (sevoflurane vs propofol) on the incidence and severity of postoperative cognitive dysfunction (POCD) in elderly patients (aged ≥ 60 years) with mild cognitive impairment (MCI). ⋯ There was no difference in the incidence of POCD at 7 days after radical rectal resection under sevoflurane or propofol-based general anaesthesia. Both propofol and sevoflurane were associated with negative cognitive effects, but sevoflurane had a more severe impact on cognitive function than propofol, in elderly patients with MCI.
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Randomized Controlled Trial Comparative Study
Effect of ketamine versus alfentanil following midazolam in preventing emergence agitation in children after sevoflurane anaesthesia: a prospective randomized clinical trial.
To investigate the effect of intranasal ketamine versus alfentanil in addition to oral midazolam for the prevention of emergence agitation in children. ⋯ The addition of intranasal ketamine to oral midazolam significantly improved the quality of induction and reduced sevoflurane-induced emergence agitation, in children undergoing urological surgery.
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Randomized Controlled Trial
Effect of heated humidified ventilation on bronchial mucus transport velocity in general anaesthesia: a randomized trial.
To evaluate the effects of heated humidified ventilation on mucociliary function during general anaesthesia. ⋯ Heated humidified ventilation effectively maintains mucociliary clearance of patients during sevoflurane general anaesthesia.