The Journal of international medical research
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Randomized Controlled Trial
Low concentrations of lidocaine for inguinal hernia repair under local infiltration anaesthesia.
A randomized, double-blind, prospective, controlled study to determine the lowest concentration of lidocaine that provides satisfactory anaesthesia and analgesia for inguinal hernia repair. ⋯ The mean dose of lidocaine consumed in group A was significantly lower but exerted similar efficacy to that in the other groups, and may lead to a lower risk of local anaesthetic toxicity.
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Randomized Controlled Trial
Association between bispectral index and age and use of sedative drugs in high spinal anaesthesia.
A prospective, randomized, double-blind study using bispectral index values to objectively quantify the sedative effect of high spinal anaesthesia in patients stratified according to age, and to determine whether sedative drugs are associated with additional adverse respiratory and haemodynamic effects in older patients. ⋯ The sedative effect of high spinal anaesthesia is greater in older patients than in younger patients, with an increase in respiratory instability.
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Randomized Controlled Trial
Target-controlled infusion of remifentanil for laryngeal mask airway insertion during sevoflurane induction in adults.
This randomized, double-blind study investigated the suitable target effect-site concentration of remifentanil for laryngeal mask airway (LMA) insertion during inhalation induction with sevoflurane. ⋯ Compared with 1 ng/ml remifentanil or normal saline, target-controlled infusion of 2 ng/ml remifentanil significantly improved the LMA insertion conditions during sevoflurane inhalational induction, although apnoeic episodes were more frequently observed.
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Randomized Controlled Trial Multicenter Study Comparative Study
Efficacy and tolerability of celecoxib versus naproxen in patients with osteoarthritis of the knee: a randomized, double-blind, double-dummy trial.
To assess the efficacy and tolerability of celecoxib versus naproxen in patients with osteoarthritis (OA) of the knee. ⋯ Over the 6month study period, celecoxib provided similar improvements in OA symptoms to naproxen. In addition, celecoxib provided better upper gastrointestinal tolerability than naproxen.
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Randomized Controlled Trial
Perioperative assessment of terlipressin infusion during living donor liver transplantation.
To investigate the safety and efficacy of infusion of terlipressin during living donor liver transplantation (LDLT). ⋯ Terlipressin infusion improved low SVRI and PVRI during LDLT and may have contributed to better renal function and shorter ICU stays.