Journal of cataract and refractive surgery
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J Cataract Refract Surg · Jan 1999
Randomized Controlled Trial Multicenter Study Comparative Study Clinical TrialEfficacy and safety of nonpreserved ketorolac ophthalmic solution in postoperative ocular pain following radial keratotomy.
To investigate the efficacy and safety of nonpreserved ketorolac tromethamine 0.5% ophthalmic solution in relieving pain following radial keratotomy (RK). ⋯ Nonpreserved ketorolac tromethamine 0.5% ophthalmic solution was significantly more effective than, and as safe as, the vehicle in alleviating the postoperative pain associated with RK. This resulted in significant improvements in patient quality of life and less need for oral analgesics, suggesting that topical ketorolac is an appropriate treatment option for ocular pain following RK.
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J Cataract Refract Surg · Dec 1998
Randomized Controlled Trial Comparative Study Clinical TrialPain in scleral pocket incision cataract surgery using topical and peribulbar anesthesia.
To evaluate the pain produced during different phases of phacoemulsification cataract surgery using a scleral pocket incision under topical versus peribulbar anesthesia. ⋯ Considering the entire procedure, total pain using topical anesthesia was acceptable and equal to that using peribulbar anesthesia for phacoemulsification with a scleral pocket incision. Pain during phacoemulsification was greater under topical anesthesia but not significantly different from the pain during the peribulbar injection.
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J Cataract Refract Surg · Dec 1998
Randomized Controlled Trial Comparative Study Clinical TrialTopical tetracaine versus topical tetracaine plus intracameral lidocaine for cataract surgery.
To compare topical tetracaine 0.5% alone and with intracameral lidocaine 1% as a local anesthetic agent in phacoemulsification with intraocular lens (IOL) implantation. ⋯ Topical tetracaine 0.5% with intracameral lidocaine was safe and effective in patients having phacoemulsification with IOL implantation. The advantage of using intracameral lidocaine 1% over a placebo was a significant decrease in the patients' subjective experience of pain and in the surgeon's satisfaction with the anesthesia used. None of the other parameters measured in this study differed significantly between the 2 groups.
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J Cataract Refract Surg · Dec 1997
Randomized Controlled Trial Comparative Study Clinical TrialSublingual lorazepam as premedication in peribulbar anesthesia.
To assess the efficacy of sublingual lorazepam in inducing amnesia when used as a premedication for peribulbar anesthesia. ⋯ Sublingual lorazepam improved patient comfort by inducing amnesia, and in the low dose used in this study, did not adversely affect surgery by undue heavy sedation.
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J Cataract Refract Surg · Nov 1997
Randomized Controlled Trial Comparative Study Clinical TrialTopical anesthesia with pH-adjusted versus standard lidocaine 4% for clear corneal cataract surgery.
To evaluate and compare the efficacy of a sodium-bicarbonate-adjusted preparation of lidocaine 4% (pH = 7.2) and standard lidocaine (pH = 5.2) for topical anesthesia in clear corneal cataract surgery. ⋯ In this study, pH-adjusted lidocaine 4% was a safe, effective topical anesthetic for clear corneal surgery and had minimal local and systemic toxicity. Administration of pH-adjusted lidocaine 4% resulted in significantly higher aqueous humor lidocaine concentrations than administration of standard lidocaine 4%.