Clinical endocrinology
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Clinical endocrinology · Mar 2001
Randomized Controlled Trial Clinical TrialInfluence of melatonin administration on glucose tolerance and insulin sensitivity of postmenopausal women.
The effect of melatonin on human carbohydrate metabolism is not yet clear. We investigated whether melatonin influences glucose tolerance and insulin sensitivity in aged women. ⋯ The present results indicate that in aged women administration of 1 mg of melatonin reduces glucose tolerance and insulin sensitivity. The present data may have both physiological and clinical implications.