Journal of general internal medicine
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Coronavirus disease 2019 (COVID-19) causes a mild illness in most cases; forecasting COVID-19-associated mortality and the demand for hospital beds and ventilators are crucial for rationing countries' resources. ⋯ We developed a new model able to predict the severity of COVID-19 in Mexican patients. This model could be helpful in epidemiology and medical decisions.
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Meta Analysis
Empirical Comparisons of 12 Meta-analysis Methods for Synthesizing Proportions of Binary Outcomes.
Meta-analysis is increasingly used to synthesize proportions (e.g., disease prevalence). It can be implemented with widely used two-step methods or one-step methods, such as generalized linear mixed models (GLMMs). Existing simulation studies have shown that GLMMs outperform the two-step methods in some settings. It is, however, unclear whether these simulation settings are common in the real world. We aim to compare the real-world performance of various meta-analysis methods for synthesizing proportions. ⋯ Although different methods produced similar overall proportion estimates in most datasets, one-step methods should be considered in the presence of small total event counts or sample sizes and very low or high event rates.
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Randomized Controlled Trial
Effect of Personalized Messages Sent by a Health System's Patient Portal on Influenza Vaccination Rates: a Randomized Clinical Trial.
Adult influenza vaccination rates are low. Tailored patient reminders might raise rates. ⋯ Patient reminders sent by a health system's patient portal that were tailored to patient demographics (young adults, older adults, diabetes) and that incorporated two behavioral economic messaging strategies (pre-commitment and loss/gain framing) were not effective in raising influenza vaccination rates.
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Multicenter Study
Characteristics of Opioid Prescribing in Non-surgical Medicine Patients with Acute Pain at Hospital Discharge.
The opioid epidemic and new Joint Commission standards around opioid stewardship have made the appropriate prescribing of opioids a priority. A knowledge gap exists pertaining to the short-term prescription of opioids at hospital discharge for acute pain in non-surgical patients. ⋯ Given the observed variation in opioid prescribing and utilization data, standardized indication-based opioid prescribing guidance in the non-surgical medical population would help curb the amount of opioids that remain unused post-discharge.