Journal of pain and symptom management
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J Pain Symptom Manage · May 2013
The effect of severe androgen deficiency on physical function in male patients with cancer.
Low circulating testosterone concentrations are commonly observed in male patients with cancer and have been shown to be associated with weight loss and increased severity of many symptoms, including fatigue and weakness. ⋯ The present study shows that in male patients with cancer, an extremely low serum free testosterone concentration is independently associated with 6-MWD but not maximal gait speed. Hence, a severe testosterone deficiency may impair their ability to perform sustained activity, but to a lesser degree, short bursts of activity.
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J Pain Symptom Manage · May 2013
Overcoming barriers to recruitment in care of the dying research in hospitals.
Approximately 40% of the U.S. and 60% of the U.K. population die in hospital. Many reports have highlighted variability in the care received by these patients and national initiatives have proposed strategies to improve this care. No studies have demonstrated whether any improvements in end-of-life care have been achieved, as research in this area is challenging. ⋯ We have shown that identifying and involving dying patients in research is possible and acceptable to patients and carers.
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J Pain Symptom Manage · May 2013
Letter Case ReportsLocked-in syndrome as a result of cyclizine administration.