International journal of colorectal disease
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Int J Colorectal Dis · Feb 2020
Efficacy of indocyanine green fluorescence angiography in preventing anastomotic leakage after laparoscopic colorectal cancer surgery.
Some recent studies have suggested that fluorescence angiography with indocyanine green (ICG) might be useful for preventing anastomotic leakage (AL) after laparoscopic colorectal surgery. However, its efficacy has not been proven. We evaluated whether intraoperative ICG fluorescence angiography could decrease the AL rate with laparoscopic colorectal cancer surgery. ⋯ ICG fluorescence angiography can potentially reduce the AL rate with laparoscopic rectal cancer surgery.
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Int J Colorectal Dis · Feb 2020
Meta AnalysisRegorafenib, TAS-102, or fruquintinib for metastatic colorectal cancer: any difference in randomized trials?
Direct randomized comparisons of regorafenib, TAS-102, and fruquintinib for treating metastatic colorectal cancer (mCRC) are lacking. Here, we evaluated the efficacy and safety of three agents by a systematic review and a network meta-analysis. ⋯ Indirect comparison suggested that the three agents had similar OS but that fruquintinib was superior in terms of PFS compared with that of TAS-102. These three agents had different toxicity profiles.