Journal of gastroenterology and hepatology
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J. Gastroenterol. Hepatol. · Apr 2011
Randomized Controlled Trial Comparative StudyVisceral sensation and irritable bowel syndrome; with special reference to comparison with functional abdominal pain syndrome.
Stress-induced visceral hypersensitivity may play an important role in the pathogenesis of irritable bowel syndrome (IBS) but not in functional abdominal pain syndrome (FAPS). We examined rectal sensation in those patients. ⋯ RRD-induced rectal hypersensitivity seems to be reliable marker for IBS, and CRF may contribute to this response. FAPS patients may have hyposensitivity to non-noxious physiological distention, suggesting FAPS has different pathogenesis from IBS.