Journal of gastroenterology and hepatology
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J. Gastroenterol. Hepatol. · Jan 2012
Multicenter StudyHealth utilities and psychometric quality of life in patients with early- and late-stage hepatitis C virus infection.
Hepatitis C virus (HCV) infection is associated with impairment in health-related quality of life (HRQOL). The purpose of this study was to evaluate HRQOL across the HCV disease spectrum using preference-based (utility) and non-preference-based (psychometric) methods, adjusting for sociodemographic factors and co-morbidity. ⋯ The effect of stage of disease on HRQOL is modest, although viral clearance is associated with higher HRQOL. HCV patients' HRQOL is strongly associated with concomitant illness and sociodemographic factors.