Journal of gastroenterology and hepatology
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J. Gastroenterol. Hepatol. · Jul 2009
Randomized Controlled Trial Comparative StudyEfficacy of a single 24-hour pre-anesthetic dose of proton pump inhibitors.
The H(2) receptor antagonist roxatidine is routinely used as an oral pre-anesthetic medication in surgical patients at night and 2 h before surgery. In the present study, we have compared the effects of roxatidine, rabeprazole and lansoprazole given singly at night as an alternative to the standard double roxatidine medication. ⋯ Single rabeprazole (but not lansoperazole) medication may be a suitable alternative to standard roxatidine for prophylaxis of acid aspiration pneumonia.
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J. Gastroenterol. Hepatol. · May 2009
Long-term outcome of endoscopic therapy in patients with bile duct injury after cholecystectomy.
Bile duct lesions, including leaks and strictures, are immanent complications of open or laparoscopic cholecystectomy. Endoscopic procedures have gained increasing potential as the treatment of choice in the management of postoperative bile duct injuries. ⋯ Endoscopic treatment of bile duct lesions after cholecystectomy is effective, particularly in patients with peripheral bile duct leakages and bile duct strictures. Therefore, it should be the first-line therapy used in these patients. Although endoscopic management is less successful in patients with central bile duct leakages, an attempt is warranted.