Current medical research and opinion
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Meta Analysis
The effects of statin on atrial fibrillation: a meta-analysis of published data from randomized controlled trials.
Some clinical and experimental studies have shown the use of statins could protect against AF, but there are not adequate data at present. ⋯ Our meta-analysis suggests that the use of statins may be associated with preventing AF in short term trials and long term trials, but in the long term trials of more intensive versus standard statin, there was no evidence of a reduction in the risk of AF. However, we still need large-scale randomized double blind statin trials with AF occurrence as the main endpoint in order to finally confirm the benefits of statin in AF patients.