Current medical research and opinion
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Randomized Controlled Trial Comparative Study
Comparison of vortioxetine versus venlafaxine XR in adults in Asia with major depressive disorder: a randomized, double-blind study.
This randomized, double-blind 8 week study compared the efficacy and tolerability of fixed-dose treatment with vortioxetine (10 mg/day) and venlafaxine extended release (XR) (150 mg/day) in major depressive disorder (MDD) patients. ⋯ Vortioxetine was at least as efficacious as venlafaxine XR and was safe and better tolerated than venlafaxine XR.