Current medical research and opinion
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Randomized Controlled Trial Multicenter Study Comparative Study
Preservative-free versus preserved latanoprost eye drops in patients with open-angle glaucoma or ocular hypertension.
This study compared the efficacy, safety, and pharmacokinetics of a preservative-free latanoprost formulation to an established, benzalkonium chloride (BAK) containing formulation for the treatment of open-angle glaucoma or ocular hypertension. ⋯ Preservative-free latanoprost showed similar efficacy at all time points compared to BAK preservative containing formulation, with no difference in tolerance, allowing progression to phase III clinical development.