Pediatric surgery international
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Pediatr. Surg. Int. · Jun 2008
Randomized Controlled Trial Comparative StudyA comparison of analgesic efficacy of tramadol and pethidine for management of postoperative pain in children: a randomized, controlled study.
Prevention of postoperative pain in children is one of the most important objectives of the anesthesiologist. Opioids have been used as an analgesic for postoperative pain in children for many years. Tramadol has both opioid and monoaminergic agonist actions. ⋯ Sedation scores, heart rate and systolic and diastolic blood pressure showed no significant differences between the groups. We conclude that pethidine and tramadol are effective in providing analgesia in pediatric patients, but pethidine provided better postoperative analgesia than tramadol. Changes in blood pressure, heart rate and arterial oxygen saturation were minimal and were similar in both drugs.