Metabolic brain disease
The most recent articles from:
December 2002
-
Metabolic brain disease · Dec 2002
ReviewHypothermia for the management of intracranial hypertension in acute liver failure.
Increased intracranial pressure in patients with acute liver failure (ALF) remains a major immediate cause of mortality. Several studies in animal models of ALF set the stage for the clinical application of moderate hypothermia in man. ⋯ Data from studies in patients undergoing liver transplantation for ALF suggest that increases in intracranial pressure can be prevented during the dissection and reperfusion phases of the operation if the patients are maintained hypothermic during surgery. The present review focuses upon the clinical aspects of using hypothermia as a treatment of increased intracranial pressure in patients with ALF.