Journal of critical care
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Journal of critical care · Apr 2024
ReviewThe physiology of cardiac tamponade and implications for patient management.
Exceeding the limit of pericardial stretch, intrapericardial collections exert compression on the right heart and decrease preload. Compensatory mechanisms ensue to maintain hemodynamics in the face of a depressed stroke volume but are outstripped as disease progresses. ⋯ Invasive hemodynamics and echocardiographic findings inform on the physiologic effects. In this review, we describe tamponade physiology and implications for supportive care and effusion drainage.
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Assessment of the IVC by point-of-care ultrasound in the context of resuscitation has been a controversial topic in the last decades. Most of the focus had been on its use as a surrogate marker for fluid responsiveness, with results being equivocal. We review its important anatomical aspects as well as the physiological rationale behind ultrasound assessment and propose a new way to do so, as well as explain its central role in the concept of fluid tolerance.
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Journal of critical care · Apr 2024
Randomized Controlled TrialEarly prediction of sepsis in intensive care patients using the machine learning algorithm NAVOY® Sepsis, a prospective randomized clinical validation study.
To prospectively validate, in an ICU setting, the prognostic accuracy of the sepsis prediction algorithm NAVOY® Sepsis which uses 4 h of input for routinely collected vital parameters, blood gas values, and lab values. ⋯ The accuracy, sensitivity, and specificity were all high, validating the prognostic accuracy of NAVOY® Sepsis in an ICU setting, including Covid-19 patients.
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Journal of critical care · Apr 2024
Prevalence of frailty and association with patient centered outcomes: A prospective registry-embedded cohort study from India.
We aimed to study the prevalence of frailty, evaluate risk factors, and understand impact on outcomes in India. ⋯ CTRI/2021/02/031503.
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Journal of critical care · Apr 2024
Multicenter StudyCannabis use disorders and outcome of admission to intensive care: A retrospective multi-centre cohort study.
To identify factors associated with cannabinoid use among patients admitted to ICU and its impact on survival. ⋯ Cannabinoid-use disorders were present in 0.8% of ICU admissions in our region and were associated with increased ICU length of stay. Further studies are needed to examine cannabinoids as contributors to and modifiers of critical illness.