Journal of critical care
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Journal of critical care · Jun 2013
Review Meta AnalysisAntipyretic therapy in febrile critically ill adults: A systematic review and meta-analysis.
To determine whether fever control with antipyretic therapy effects the mortality of febrile critically ill adults. ⋯ This meta-analysis found no evidence that fever treatment influences mortality in critically ill adults without acute neurological injury. However, studies were underpowered to detect clinically important differences.
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Journal of critical care · Jun 2013
Improving the 2007 Infectious Disease Society of America/American Thoracic Society severe community-acquired pneumonia criteria to predict intensive care unit admission.
To improve 2007 Infectious Disease Society of America/American Thoracic Society (IDSA/ATS) severity criteria to predict intensive care unit (ICU) admission in patients hospitalized with pneumonia. ⋯ The addition of arterial pH <7.30 to the 2007 IDSA/ATS major criteria improves sensitivity and AUC to identify patients who will require ICU care.
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Journal of critical care · Jun 2013
Perioperative plasma melatonin concentration in postoperative critically ill patients: its association with delirium.
Delirium is a common complication in postoperative critically ill patients. Although abnormal melatonin metabolism is thought to be one of the mechanisms of delirium, there have been few studies in which the association between alteration of perioperative plasma melatonin concentration and postoperative delirium was assessed. ⋯ Delta melatonin concentration at 1 hour after the operation has a significant independent association with risk of postoperative delirium.
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Journal of critical care · Jun 2013
Drug-drug interactions contributing to QT prolongation in cardiac intensive care units.
To determine the most common drug-drug interaction (DDI) pairs contributing to QTc prolongation in cardiac intensive care units (ICUs). ⋯ DDIs may be a significant cause of QT prolongation in cardiac ICUs. These data can be used to educate clinicians on safe medication use. Computerized clinical decision support could be applied to aid in the detection of these events.
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Journal of critical care · Jun 2013
ReviewNonpharmacologic interventions for prevention of catheter-related thrombosis: a systematic review.
The aim of this study was to summarize randomized controlled trials (RCTs) of nonpharmacologic interventions for prevention of catheter-related thromboses (CRTs). ⋯ Peripherally inserted central catheters and femoral insertion of CVCs should be avoided if possible. Randomized controlled trials are needed to ascertain the effects of other nonpharmacologic interventions to prevent CRT.