Journal of critical care
-
Journal of critical care · Dec 2015
Randomized Controlled Trial Multicenter StudyImpact of endotracheal intubation on septic shock outcome: A post hoc analysis of the SEPSISPAM trial.
The objective of the study to is to determine the characteristics associated with endotracheal intubation in septic shock patients. ⋯ Practices regarding the place of endotracheal intubation in septic shock may impact outcome.
-
Altered mental status is a common pathological entity in critically ill patients and particularly in those with preexisting cerebral injury. In the neurological critical care unit, the prevalence of altered mental status is especially high because of the inherent nervous system disease of these patients. ⋯ Although often used interchangeably, the 2 pathological entities have subtle differences in etiology and presentation. This is a review of delirium and encephalopathy in the neurological critical care unit.
-
Journal of critical care · Dec 2015
Observational StudyWhole-blood neutrophil gelatinase-associated lipocalin to predict adverse events in acute kidney injury: A prospective observational cohort study.
Acute kidney injury is common in intensive care units and is associated with increased morbidity and mortality. We evaluated the ability of whole-blood neutrophil gelatinase-associated lipocalin (wbNGAL) to predict mortality and need for renal replacement therapy (RRT) in critically ill patients with kidney dysfunction. ⋯ In a cohort of critically ill patients with abnormal kidney function, wbNGAL was not effective in the prediction of death or RRT within 30 days. These data do not support the use of this biomarker for the detection of clinical outcomes in this population.
-
Journal of critical care · Dec 2015
Observational StudyAssessment of muscle tissue oxygen saturation after out-of-hospital cardiac arrest.
Pathophysiology of cardiac arrest corresponds to an ischemia-reperfusion syndrome with deep impairment of microcirculation. Muscular tissue oxygen saturation (StO2) is a noninvasive method of evaluation of microcirculation. Our study was aimed at assessing the prognosis value of muscular StO2 in patients admitted for out-of-hospital cardiac arrest (OHCA) and treated with hypothermia. ⋯ After an OHCA treated with therapeutic hypothermia, StO2 was correlated with outcome. Further research is needed to better understand the pathophysiological process underlying our results.